A soluble activin type IIA receptor induces bone formation and improves skeletal integrity

Diseases that affect the regulation of bone turnover can lead to skeletal fragility and increased fracture risk. Members of the TGF-β superfamily have been shown to be involved in the regulation of bone mass. Activin A, a TGF-β signaling ligand, is present at high levels in bone and may play a role...

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Autori principali: Pearsall, R. Scott, Canalis, Ernesto, Cornwall-Brady, Milton, Underwood, Kathryn W., Haigis, Brendan, Ucran, Jeffrey, Kumar, Ravindra, Pobre, Eileen, Grinberg, Asya, Werner, Eric D., Glatt, Vaida, Stadmeyer, Lisa, Smith, Deanna, Seehra, Jasbir, Bouxsein, Mary L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2008
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2383948/
https://ncbi.nlm.nih.gov/pubmed/18460605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0711263105
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