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Cloning and characterization of a mammalian 8-oxoguanine DNA glycosylase

Oxidative DNA damage is generated by reactive oxygen species. The mutagenic base, 8-oxoguanine, formed by this process, is removed from oxidatively damaged DNA by base excision repair. Genes coding for DNA repair enzymes that recognize 8-oxoguanine have been reported in bacteria and yeast. We have i...

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Bibliografische gegevens
Hoofdauteurs: Rosenquist, Thomas A., Zharkov, Dmitry O., Grollman, Arthur P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The National Academy of Sciences of the USA 1997
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC23838/
https://ncbi.nlm.nih.gov/pubmed/9207108
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