A functional GTP-binding motif is necessary for antiviral activity of Mx proteins.

Mx proteins are interferon-induced GTPases that inhibit the multiplication of certain negative-stranded RNA viruses. However, it has been unclear whether GTPase activity is necessary for antiviral function. Here, we have introduced mutations into the tripartite GTP-binding consensus elements of the...

Descrición completa

Detalles Bibliográficos

Publicado en:	J Virol
Principais autores:	Pitossi, F, Blank, A, Schröder, A, Schwarz, A, Hüssi, P, Schwemmle, M, Pavlovic, J, Staeheli, P
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology (ASM) 1993
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC238112/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8411374/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.11.6726-6732.1993
Tags:	Engadir etiqueta Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!