A functional GTP-binding motif is necessary for antiviral activity of Mx proteins.
Mx proteins are interferon-induced GTPases that inhibit the multiplication of certain negative-stranded RNA viruses. However, it has been unclear whether GTPase activity is necessary for antiviral function. Here, we have introduced mutations into the tripartite GTP-binding consensus elements of the...
Збережено в:
| Опубліковано в:: | J Virol |
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| Автори: | , , , , , , , |
| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
American Society for Microbiology (ASM)
1993
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| Предмети: | |
| Онлайн доступ: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC238112/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8411374/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.11.6726-6732.1993 |
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