A functional GTP-binding motif is necessary for antiviral activity of Mx proteins.

Mx proteins are interferon-induced GTPases that inhibit the multiplication of certain negative-stranded RNA viruses. However, it has been unclear whether GTPase activity is necessary for antiviral function. Here, we have introduced mutations into the tripartite GTP-binding consensus elements of the...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Pitossi, F, Blank, A, Schröder, A, Schwarz, A, Hüssi, P, Schwemmle, M, Pavlovic, J, Staeheli, P
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 1993
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC238112/
https://ncbi.nlm.nih.gov/pubmed/8411374
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