Monoclonal antibodies that disrupt poliovirus only at fever temperatures.

Three of thirty-six monoclonal antibodies were found to cause irreversible inactivation of type 1 poliovirus at 39 degrees C but not at 37 degrees C. Neutralization at 37 degrees C depended on aggregation and was reversible by acid-induced deaggregation; at 39 degrees C, the virions (N antigenic, 16...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Delaet, I, Boeyé, A
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1993
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237928/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8394450/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.9.5299-5302.1993
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