Monoclonal antibodies that disrupt poliovirus only at fever temperatures.
Three of thirty-six monoclonal antibodies were found to cause irreversible inactivation of type 1 poliovirus at 39 degrees C but not at 37 degrees C. Neutralization at 37 degrees C depended on aggregation and was reversible by acid-induced deaggregation; at 39 degrees C, the virions (N antigenic, 16...
Guardat en:
| Publicat a: | J Virol |
|---|---|
| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology (ASM)
1993
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237928/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8394450/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.9.5299-5302.1993 |
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