Monoclonal antibodies that disrupt poliovirus only at fever temperatures.

Three of thirty-six monoclonal antibodies were found to cause irreversible inactivation of type 1 poliovirus at 39 degrees C but not at 37 degrees C. Neutralization at 37 degrees C depended on aggregation and was reversible by acid-induced deaggregation; at 39 degrees C, the virions (N antigenic, 16...

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Veröffentlicht in:	J Virol
Hauptverfasser:	Delaet, I, Boeyé, A
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1993
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237928/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8394450/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.9.5299-5302.1993
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