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Monoclonal antibodies that disrupt poliovirus only at fever temperatures.

Three of thirty-six monoclonal antibodies were found to cause irreversible inactivation of type 1 poliovirus at 39 degrees C but not at 37 degrees C. Neutralization at 37 degrees C depended on aggregation and was reversible by acid-induced deaggregation; at 39 degrees C, the virions (N antigenic, 16...

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Библиографические подробности
Главные авторы: Delaet, I, Boeyé, A
Формат: Artigo
Язык:Inglês
Опубликовано: 1993
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC237928/
https://ncbi.nlm.nih.gov/pubmed/8394450
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