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Applications for ROCK kinase inhibition
ROCK kinases, which play central roles in the organization of the actin cytoskeleton, are tantalizing targets for the treatment of human diseases. Deletion of ROCK I in mice revealed a role in the pathophysiological responses to high blood pressure, and validated ROCK inhibition for the treatment of...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2377343/ https://ncbi.nlm.nih.gov/pubmed/18282695 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2008.01.002 |
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