The mitogenic activity of human T-cell leukemia virus type I is T-cell associated and requires the CD2/LFA-3 activation pathway.

The presence of a high number of activated T cells in the bloodstream and spontaneous proliferation of peripheral blood mononuclear cells in vitro are striking characteristics of human T-cell leukemia virus type I (HTLV-I) infection. The HTLV-I regulatory protein Tax and the envelope protein gp46 ha...

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Publicado en:	J Virol
Autores principales:	Kimata, J T, Palker, T J, Ratner, L
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 1993
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237651/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7684460/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.6.3134-3141.1993
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