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The mitogenic activity of human T-cell leukemia virus type I is T-cell associated and requires the CD2/LFA-3 activation pathway.

The presence of a high number of activated T cells in the bloodstream and spontaneous proliferation of peripheral blood mononuclear cells in vitro are striking characteristics of human T-cell leukemia virus type I (HTLV-I) infection. The HTLV-I regulatory protein Tax and the envelope protein gp46 ha...

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Bibliografiska uppgifter
Huvudupphovsmän: Kimata, J T, Palker, T J, Ratner, L
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1993
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC237651/
https://ncbi.nlm.nih.gov/pubmed/7684460
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