A Phase I clinical and pharmacological study of cis-diamminedichloro(2-methylpyridine) platinum II (AMD473)

AMD473 is a novel sterically hindered platinum cytotoxic with demonstrated ability to overcome acquired resistance to cisplatin in vitro and in human tumour xenografts. A single-agent dose escalating Phase I study was performed. AMD473 was initially administered intravenously as a 1 h infusion every...

Fuld beskrivelse

Na minha lista:

Bibliografiske detaljer
Main Authors:	Beale, P, Judson, I, O'Donnell, A, Trigo, J, Rees, C, Raynaud, F, Turner, A, Simmons, L, Etterley, L
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Publishing Group 2003
Fag:	Experimental Therapeutics
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC2376375/ https://ncbi.nlm.nih.gov/pubmed/12671715 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600854
Tags:	Tilføj Tag Ingen Tags, Vær først til at tagge denne postø!

A Phase I clinical and pharmacological study of cis-diamminedichloro(2-methylpyridine) platinum II (AMD473)

Lignende værker