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Synthesis and activity of three new trinuclear platinums with cis-geometry for terminal metal centres
BACKGROUND: As compared to cisplatin, trinuclear platinum compounds such as BBR3464 and DH6Cl have an altered spectrum of activity possibly because they form long-range adducts with DNA as against mainly intrastrand 1,2-bifunctional adducts formed by cisplatin and its analogues. Because of the labil...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4022405/ https://ncbi.nlm.nih.gov/pubmed/24884683 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1423-0127-21-41 |
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