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Protection from High Fat Diet-induced Increase in Ceramide in Mice Lacking Plasminogen Activator Inhibitor 1

Obesity increases the risk for metabolic and cardiovascular disease, and adipose tissue plays a central role in this process. Ceramide, the key intermediate of sphingolipid metabolism, also contributes to obesity-related disorders. We show that a high fat diet increased ceramide levels in the adipos...

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Detalhes bibliográficos
Main Authors: Shah, Charmi, Yang, Guang, Lee, Ian, Bielawski, Jacek, Hannun, Yusuf A., Samad, Fahumiya
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2376236/
https://ncbi.nlm.nih.gov/pubmed/18359942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M709950200
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