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Corticostriatal synaptic function in mouse models of Huntington's disease: early effects of huntingtin repeat length and protein load
Huntington's disease (HD) is an autosomal dominant, late onset, neurodegenerative disease characterized by motor deficits and dementia that is caused by expansion of a CAG repeat in the HD gene. Clinical manifestations result from selective neuronal degeneration of predominantly GABAergic stria...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Blackwell Science Inc
2007
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2375504/ https://ncbi.nlm.nih.gov/pubmed/17947312 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2007.142448 |
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