Immunological protein expression profile in Ccl2/Cx3cr1 deficient mice with lesions similar to age-related macular degeneration

Age-related macular degeneration (AMD) is the leading cause of blindness in the United States. Ccl2 knock-out (KO) mice sporadically develop the cardinal features of AMD in their senescent stage. Humans bearing a loss of function variant or single nucleotide polymorphism (SNP) in CX3CR1 are at incre...

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Autores principales: Ross, Robert J., Zhou, Min, Shen, Defen, Fariss, Robert N., Ding, Xiaoyan, Bojanowski, Christine M., Tuo, Jingsheng, Chan, Chi-Chao
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2375389/
https://ncbi.nlm.nih.gov/pubmed/18308304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2008.01.014
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