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Proteasomal Degradation of TRIM5α during Retrovirus Restriction
The host protein TRIM5α inhibits retroviral infection at an early post-penetration stage by targeting the incoming viral capsid. While the detailed mechanism of restriction remains unclear, recent studies have implicated the activity of cellular proteasomes in the restriction of retroviral reverse t...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2008
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2374908/ https://ncbi.nlm.nih.gov/pubmed/18497858 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000074 |
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