Replicative Senescence of Mesenchymal Stem Cells: A Continuous and Organized Process

Mesenchymal stem cells (MSC) comprise a promising tool for cellular therapy. These cells are usually culture expanded prior to their application. However, a precise molecular definition of MSC and the sequel of long-term in vitro culture are yet unknown. In this study, we have addressed the impact o...

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Main Authors: Wagner, Wolfgang, Horn, Patrick, Castoldi, Mirco, Diehlmann, Anke, Bork, Simone, Saffrich, Rainer, Benes, Vladimir, Blake, Jonathon, Pfister, Stefan, Eckstein, Volker, Ho, Anthony D.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2008
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2374903/
https://ncbi.nlm.nih.gov/pubmed/18493317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002213
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