Aging and Replicative Senescence Have Related Effects on Human Stem and Progenitor Cells

The regenerative potential diminishes with age and this has been ascribed to functional impairments of adult stem cells. Cells in culture undergo senescence after a certain number of cell divisions whereby the cells enlarge and finally stop proliferation. This observation of replicative senescence h...

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Detaylı Bibliyografya
Asıl Yazarlar: Wagner, Wolfgang, Bork, Simone, Horn, Patrick, Krunic, Damir, Walenda, Thomas, Diehlmann, Anke, Benes, Vladimir, Blake, Jonathon, Huber, Franz-Xaver, Eckstein, Volker, Boukamp, Petra, Ho, Anthony D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2009
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2688074/
https://ncbi.nlm.nih.gov/pubmed/19513108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005846
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