Replicative senescence-associated gene expression changes in mesenchymal stromal cells are similar under different culture conditions

BACKGROUND: Research on mesenchymal stromal cells has created high expectations for a variety of therapeutic applications. Extensive propagation to yield enough mesenchymal stromal cells for therapy may result in replicative senescence and thus hamper long-term functionality in vivo. Highly variable...

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Detalhes bibliográficos
Main Authors: Schallmoser, Katharina, Bartmann, Christina, Rohde, Eva, Bork, Simone, Guelly, Christian, Obenauf, Anna C., Reinisch, Andreas, Horn, Patrick, Ho, Anthony D., Strunk, Dirk, Wagner, Wolfgang
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2010
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878782/
https://ncbi.nlm.nih.gov/pubmed/20053868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2009.011692
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