Functioning of the dimeric GABA(B) receptor extracellular domain revealed by glycan wedge scanning

The G-protein-coupled receptor (GPCR) activated by the neurotransmitter GABA is made up of two subunits, GABA(B1) and GABA(B2). GABA(B1) binds agonists, whereas GABA(B2) is required for trafficking GABA(B1) to the cell surface, increasing agonist affinity to GABA(B1), and activating associated G pro...

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Xehetasun bibliografikoak
Egile Nagusiak: Rondard, Philippe, Huang, Siluo, Monnier, Carine, Tu, Haijun, Blanchard, Bertrand, Oueslati, Nadia, Malhaire, Fanny, Li, Ying, Trinquet, Eric, Labesse, Gilles, Pin, Jean-Philippe, Liu, Jianfeng
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2008
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2374841/
https://ncbi.nlm.nih.gov/pubmed/18388862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.64
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