Identification of a DNA-binding domain in the amino terminus of adeno-associated virus Rep proteins.

The Rep78 and Rep68 proteins of adeno-associated virus (AAV) bind to the AAV terminal repeat hairpin DNA and are required for viral replication. We have expressed a series of mutant rep genes from the human immunodeficiency virus type 1 long terminal repeat promoter in human 293 cells and in an in v...

Descrizione completa

Dettagli Bibliografici

Pubblicato in:	J Virol
Autori principali:	Owens, R A, Weitzman, M D, Kyöstiö, S R, Carter, B J
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1993
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237454/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8380475/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.2.997-1005.1993
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!