Identification of a DNA-binding domain in the amino terminus of adeno-associated virus Rep proteins.
The Rep78 and Rep68 proteins of adeno-associated virus (AAV) bind to the AAV terminal repeat hairpin DNA and are required for viral replication. We have expressed a series of mutant rep genes from the human immunodeficiency virus type 1 long terminal repeat promoter in human 293 cells and in an in v...
Uloženo v:
| Vydáno v: | J Virol |
|---|---|
| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Microbiology (ASM)
1993
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237454/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8380475/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.2.997-1005.1993 |
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