Analysis of adeno-associated virus (AAV) wild-type and mutant Rep proteins for their abilities to negatively regulate AAV p5 and p19 mRNA levels.

The rep gene of adeno-associated virus type 2 (AAV) encodes four overlapping Rep proteins that are involved in gene regulation and replication of the virus. We studied here the regulation of mRNA transcribed from the AAV p5 and p19 promoters, using transient expression in human 293 cells followed by...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Kyöstiö, S R, Owens, R A, Weitzman, M D, Antoni, B A, Chejanovsky, N, Carter, B J
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1994
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC236783/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8151765/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.5.2947-2957.1994
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