Analysis of adeno-associated virus (AAV) wild-type and mutant Rep proteins for their abilities to negatively regulate AAV p5 and p19 mRNA levels.

The rep gene of adeno-associated virus type 2 (AAV) encodes four overlapping Rep proteins that are involved in gene regulation and replication of the virus. We studied here the regulation of mRNA transcribed from the AAV p5 and p19 promoters, using transient expression in human 293 cells followed by...

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Vydáno v:J Virol
Hlavní autoři: Kyöstiö, S R, Owens, R A, Weitzman, M D, Antoni, B A, Chejanovsky, N, Carter, B J
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 1994
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC236783/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8151765/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.5.2947-2957.1994
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