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Decreased GTPase activity of K- ras mutants deriving from human functional adrenocortical tumours

Our previous studies have shown that seven out of 15 patients with adrenocortical tumours contained K- ras gene mutation. In addition, the mutation type was a multiple-site mutation, and the hot spots were located at codons 15, 16, 18 and 31, which were different from those reported before (codons 1...

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Autori principali: Lin, S-R, Hsu, C-H, Tsai, J-H, Wang, J-Y, Hsieh, T-J, Wu, C-H
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2000
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2374427/
https://ncbi.nlm.nih.gov/pubmed/10737386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.1999.1039
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