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Intragenic complementation of herpes simplex virus ICP8 DNA-binding protein mutants.

The major DNA-binding protein, or infected-cell protein 8 (ICP8), of herpes simplex virus is required for viral DNA synthesis and normal regulation of viral gene expression. Previous genetic analysis has indicated that the carboxyl-terminal 28 residues are the only portion of ICP8 capable of acting...

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Bibliographic Details
Published in:J Virol
Main Authors: Gao, M, Knipe, D M
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1993
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237441/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8380469/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.2.876-885.1993
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