Sulfated polyanion inhibition of scrapie-associated PrP accumulation in cultured cells.
The accumulation of an abnormal, protease-resistant form of the protein PrP (PrP-res) in hosts with scrapie and related transmissible spongiform encephalopathies appears to be important in disease pathogenesis. To gain insight into the mechanism of PrP-res accumulation and the in vivo antiscrapie ac...
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| Published in: | J Virol |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Microbiology (ASM)
1993
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237415/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7678300/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.2.643-650.1993 |
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