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Sulfated polyanion inhibition of scrapie-associated PrP accumulation in cultured cells.

The accumulation of an abnormal, protease-resistant form of the protein PrP (PrP-res) in hosts with scrapie and related transmissible spongiform encephalopathies appears to be important in disease pathogenesis. To gain insight into the mechanism of PrP-res accumulation and the in vivo antiscrapie ac...

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Detalles Bibliográficos
Publicado en:J Virol
Principais autores: Caughey, B, Raymond, G J
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1993
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237415/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7678300/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.2.643-650.1993
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