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Sulfated polyanion inhibition of scrapie-associated PrP accumulation in cultured cells.

The accumulation of an abnormal, protease-resistant form of the protein PrP (PrP-res) in hosts with scrapie and related transmissible spongiform encephalopathies appears to be important in disease pathogenesis. To gain insight into the mechanism of PrP-res accumulation and the in vivo antiscrapie ac...

詳細記述

保存先:
書誌詳細
主要な著者: Caughey, B, Raymond, G J
フォーマット: Artigo
言語:Inglês
出版事項: 1993
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC237415/
https://ncbi.nlm.nih.gov/pubmed/7678300
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