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Strain-specified relative conformational stability of the scrapie prion protein

Studies of prion biology and diseases have elucidated several new concepts, but none was more heretical than the proposal that the biological properties that distinguish different prion strains are enciphered in the disease-causing prion protein (PrP(Sc)). To explore this postulate, we examined the...

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Auteurs principaux: Peretz, David, Scott, Michael R., Groth, Darlene, Williamson, R. Anthony, Burton, Dennis R., Cohen, Fred E., Prusiner, Stanley B.
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2001
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2373967/
https://ncbi.nlm.nih.gov/pubmed/11274476
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