Inhibition of Apoptosis in Prostate Cancer Cells by Androgens Is Mediated through Downregulation of c-Jun N-terminal Kinase Activation

Androgen deprivation induces the regression of prostate tumors mainly due to an increase in the apoptosis rate; however, the molecular mechanisms underlying the antiapoptotic actions of androgens are not completely understood. We have studied the antiapoptotic effects of androgens in prostate cancer...

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Bibliographic Details
Main Authors: Lorenzo, Petra Isabel, Saatcioglu, Fahri
Format: Artigo
Language:Inglês
Published: Neoplasia Press Inc. 2008
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2373916/
https://ncbi.nlm.nih.gov/pubmed/18472959
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