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Modulation of hepatic fibrosis by c-Jun-N-terminal kinase inhibition
BACKGROUND & AIMS: c-Jun N-terminal kinase (JNK) is activated by multiple profibrogenic mediators; JNK activation occurs during toxic, metabolic, and autoimmune liver injury. However, its role in hepatic fibrogenesis is unknown. METHODS: JNK phosphorylation was detected by immunoblot analysis an...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2988578/ https://ncbi.nlm.nih.gov/pubmed/19782079 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2009.09.015 |
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