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Modulation of hepatic fibrosis by c-Jun-N-terminal kinase inhibition

BACKGROUND & AIMS: c-Jun N-terminal kinase (JNK) is activated by multiple profibrogenic mediators; JNK activation occurs during toxic, metabolic, and autoimmune liver injury. However, its role in hepatic fibrogenesis is unknown. METHODS: JNK phosphorylation was detected by immunoblot analysis an...

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書誌詳細
主要な著者: Kluwe, Johannes, Pradere, Jean-Philippe, Gwak, Geum-Youn, Mencin, Ali, Minicis, Samuele De, Osterreicher, Christoph H., Colmenero, Jordi, Bataller, Ramon, Schwabe, Robert F.
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2988578/
https://ncbi.nlm.nih.gov/pubmed/19782079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2009.09.015
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