Different Mutant/Wild-Type p53 Combinations Cause a Spectrum of Increased Invasive Potential in Nonmalignant Immortalized Human Mammary Epithelial Cells

Aberrations of p53 occur in most, if not all, human cancers. In breast cancer, p53 mutation is the most common genetic defect related to a single gene. Immortalized human mammary epithelial cells resemble the earliest forms of aberrant breast tissue growth but do not express many malignancy-associat...

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Detaylı Bibliyografya
Asıl Yazarlar: Junk, Damian J, Vrba, Lukas, Watts, George S, Oshiro, Marc M, Martinez, Jesse D, Futscher, Bernard W
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Neoplasia Press Inc. 2008
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2373910/
https://ncbi.nlm.nih.gov/pubmed/18472962
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