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Molecular dynamics simulations of alanine rich β-sheet oligomers: Insight into amyloid formation

The aggregation observed in protein conformational diseases is the outcome of significant new β-sheet structure not present in the native state. Peptide model systems have been useful in studies of fibril aggregate formation. Experimentally, it was found that a short peptide AGAAAAGA is one of the m...

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Detalhes bibliográficos
Main Authors: Ma, Buyong, Nussinov, Ruth
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2373704/
https://ncbi.nlm.nih.gov/pubmed/12237456
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