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Molecular dynamics simulations of alanine rich β-sheet oligomers: Insight into amyloid formation
The aggregation observed in protein conformational diseases is the outcome of significant new β-sheet structure not present in the native state. Peptide model systems have been useful in studies of fibril aggregate formation. Experimentally, it was found that a short peptide AGAAAAGA is one of the m...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Cold Spring Harbor Laboratory Press
2002
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2373704/ https://ncbi.nlm.nih.gov/pubmed/12237456 |
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