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Bacterial expression and membrane targeting of the rat complement regulator Crry: A new model anticomplement therapeutic

Inappropriate or unregulated activation of complement can contribute to pathology in inflammatory diseases. Previous studies have shown that soluble recombinant regulators of complement are effective in animal models and some human diseases. However, limitations include cost, rapid clearance, and un...

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Библиографические подробности
Главные авторы: Fraser, Deborah A., Harris, Claire L., Smith, Richard A.G., Morgan, B. Paul
Формат: Artigo
Язык:Inglês
Опубликовано: Cold Spring Harbor Laboratory Press 2002
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2373695/
https://ncbi.nlm.nih.gov/pubmed/12237472
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