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Bacterial expression and membrane targeting of the rat complement regulator Crry: A new model anticomplement therapeutic

Inappropriate or unregulated activation of complement can contribute to pathology in inflammatory diseases. Previous studies have shown that soluble recombinant regulators of complement are effective in animal models and some human diseases. However, limitations include cost, rapid clearance, and un...

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Detalhes bibliográficos
Main Authors: Fraser, Deborah A., Harris, Claire L., Smith, Richard A.G., Morgan, B. Paul
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2373695/
https://ncbi.nlm.nih.gov/pubmed/12237472
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