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Complement-dependent T-cell lymphopenia caused by thymocyte deletion of the membrane complement regulator Crry

Although complement lysis is frequently used for the purification of lymphocyte subpopulations in vitro, how lymphocytes escape complement attack in vivo has not been clearly delineated. Here, we show that conditional gene targeting of a murine membrane complement regulator Crry on thymocytes led to...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Miwa, Takashi, Zhou, Lin, Kimura, Yuko, Kim, David, Bhandoola, Avinash, Song, Wen-Chao
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2661856/
https://ncbi.nlm.nih.gov/pubmed/19136662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-05-157966
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