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Complement-dependent T-cell lymphopenia caused by thymocyte deletion of the membrane complement regulator Crry

Although complement lysis is frequently used for the purification of lymphocyte subpopulations in vitro, how lymphocytes escape complement attack in vivo has not been clearly delineated. Here, we show that conditional gene targeting of a murine membrane complement regulator Crry on thymocytes led to...

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Detalhes bibliográficos
Main Authors: Miwa, Takashi, Zhou, Lin, Kimura, Yuko, Kim, David, Bhandoola, Avinash, Song, Wen-Chao
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2661856/
https://ncbi.nlm.nih.gov/pubmed/19136662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-05-157966
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