Učitavanje...

Genetic and therapeutic targeting of properdin in mice prevents complement-mediated tissue injury

The alternative pathway (AP) of complement activation is constitutively active and must be regulated by host proteins to prevent autologous tissue injury. Dysfunction of AP regulatory proteins has been linked to several human inflammatory disorders. Properdin is a positive regulator of AP complement...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Glavni autori: Kimura, Yuko, Zhou, Lin, Miwa, Takashi, Song, Wen-Chao
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947218/
https://ncbi.nlm.nih.gov/pubmed/20941861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI41782
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!