Nalaganje...
Genetic and therapeutic targeting of properdin in mice prevents complement-mediated tissue injury
The alternative pathway (AP) of complement activation is constitutively active and must be regulated by host proteins to prevent autologous tissue injury. Dysfunction of AP regulatory proteins has been linked to several human inflammatory disorders. Properdin is a positive regulator of AP complement...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Clinical Investigation
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2947218/ https://ncbi.nlm.nih.gov/pubmed/20941861 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI41782 |
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