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Membrane protein Crry maintains homeostasis of the complement system

Complement activation is tightly regulated to avoid excessive inflammatory and immune responses. Crry(-/-) is an embryonic lethal phenotype secondary to the maternal complement alternative pathway (AP) attacking a placenta deficient in this inhibitor. In this study, we demonstrate that Crry(-/-) mic...

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Detalhes bibliográficos
Main Authors: Wu, Xiaobo, Spitzer, Dirk, Mao, Dailing, Peng, Stanford L., Molina, Hector, Atkinson, John P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2580744/
https://ncbi.nlm.nih.gov/pubmed/18684964
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