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Properdin homeostasis requires turnover of the alternative complement pathway

Properdin is a plasma protein and is also released from neutrophil granules following stimulation. At inflammatory sites it can bind bacteria and apoptotic bodies to trigger alternative pathway (AP) activation. Principles governing properdin homeostasis are unknown. We monitored properdin during AP...

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Bibliografische gegevens
Hoofdauteurs: Wu, Xiaobo, Xu, Thomas Q., Atkinson, John P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2984156/
https://ncbi.nlm.nih.gov/pubmed/20974943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1006608107
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