PR-Set7–dependent lysine methylation ensures genome replication and stability through S phase

PR-Set7/SET8 is a histone H4–lysine 20 methyltransferase required for normal cell proliferation. However, the exact functions of this enzyme remain to be determined. In this study, we show that human PR-Set7 functions during S phase to regulate cellular proliferation. PR-Set7 associates with replica...

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Main Authors: Tardat, Mathieu, Murr, Rabih, Herceg, Zdenko, Sardet, Claude, Julien, Eric
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2007
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Research Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2373513/
https://ncbi.nlm.nih.gov/pubmed/18158331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200706179
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