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Methylation of histone H4 lysine 20 by PR-Set7 ensures the integrity of late replicating sequence domains in Drosophila

The methylation state of lysine 20 on histone H4 (H4K20) has been linked to chromatin compaction, transcription, DNA repair and DNA replication. Monomethylation of H4K20 (H4K20me1) is mediated by the cell cycle-regulated histone methyltransferase PR-Set7. PR-Set7 depletion in mammalian cells results...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Li, Yulong, Armstrong, Robin L., Duronio, Robert J., MacAlpine, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5009726/
https://ncbi.nlm.nih.gov/pubmed/27131378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw333
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