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PR-Set7–dependent lysine methylation ensures genome replication and stability through S phase
PR-Set7/SET8 is a histone H4–lysine 20 methyltransferase required for normal cell proliferation. However, the exact functions of this enzyme remain to be determined. In this study, we show that human PR-Set7 functions during S phase to regulate cellular proliferation. PR-Set7 associates with replica...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
The Rockefeller University Press
2007
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2373513/ https://ncbi.nlm.nih.gov/pubmed/18158331 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200706179 |
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