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Histone H4K20 tri‐methylation at late‐firing origins ensures timely heterochromatin replication
Among other targets, the protein lysine methyltransferase PR‐Set7 induces histone H4 lysine 20 monomethylation (H4K20me1), which is the substrate for further methylation by the Suv4‐20h methyltransferase. Although these enzymes have been implicated in control of replication origins, the specific con...
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| Veröffentlicht in: | EMBO J |
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| Hauptverfasser: | , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
John Wiley and Sons Inc.
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5599798/ https://ncbi.nlm.nih.gov/pubmed/28778956 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201796541 |
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