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Atrx promotes heterochromatin formation at retrotransposons

More than 50% of mammalian genomes consist of retrotransposon sequences. Silencing of retrotransposons by heterochromatin is essential to ensure genomic stability and transcriptional integrity. Here, we identified a short sequence element in intracisternal A particle (IAP) retrotransposons that is s...

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Detalhes bibliográficos
Publicado no:EMBO Rep
Main Authors: Sadic, Dennis, Schmidt, Katharina, Groh, Sophia, Kondofersky, Ivan, Ellwart, Joachim, Fuchs, Christiane, Theis, Fabian J, Schotta, Gunnar
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4515123/
https://ncbi.nlm.nih.gov/pubmed/26012739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201439937
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