Histone H4K20 tri‐methylation at late‐firing origins ensures timely heterochromatin replication

Among other targets, the protein lysine methyltransferase PR‐Set7 induces histone H4 lysine 20 monomethylation (H4K20me1), which is the substrate for further methylation by the Suv4‐20h methyltransferase. Although these enzymes have been implicated in control of replication origins, the specific con...

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Enregistré dans:
Détails bibliographiques
Publié dans:EMBO J
Auteurs principaux: Brustel, Julien, Kirstein, Nina, Izard, Fanny, Grimaud, Charlotte, Prorok, Paulina, Cayrou, Christelle, Schotta, Gunnar, Abdelsamie, Alhassan F, Déjardin, Jérôme, Méchali, Marcel, Baldacci, Giuseppe, Sardet, Claude, Cadoret, Jean‐Charles, Schepers, Aloys, Julien, Eric
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2017
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5599798/
https://ncbi.nlm.nih.gov/pubmed/28778956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201796541
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